This issue is caused by a missing printer in the LOTS printer setup, or where a formal printer has not yet been configured in LOTS for the particular printing task. For example, in this case the orange box is displayed when printing A5 Reports.
To fix this go to LOTS Main Menu > TOOLS > PRINTER SETUP and select the appropriate printer for the module which the orange box is appearing. e.g POS reports , Dispense repeats , Docket, Shelf or Goods label and so on.
You can tell which printers are not yet formally set as they will have “Defaulting to : xxxx” , meaning that LOTS is making a guess as to the appropriate printer as none has otherwise been selected.